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MagForce AG is a publicly traded German company based in Berlin, Germany that develops medical devices that generate magnetic hyperthermia to treat cancer. The company was founded in 1997 as a spin-off from Charité. [1] The medical technology company conducts research in the field of nano medicine.
In photothermal cancer therapy, many gold nanoparticle molecules are used in each test and they must all be uniform in size. Including PEG coating, the nanoparticles measured to be ~130 nm in diameter. [1] Gold nanoparticles that act as drug delivery systems in conjugation with chemotherapeutic drugs typically range in size from 10 to 100 nm. [2]
Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer compound made from the monomer N-vinylpyrrolidone. [1] PVP is available in a range of molecular weights and related viscosities, and can be selected according to the desired application properties.
In prostate cancer, the androgen receptor (AR) plays a critical role in progression of the cancer. Lipid nanoparticles (LNPs) are being considered for delivering siRNA to silence AR. The most effective LNP to be found in vivo contains an ionizable cationic lipid 2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane (DLin-KC2-DMA). [4]
Nanomedicine is the medical application of nanotechnology. [1] Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines.
Currently, inositol hexaphosphate, which is available over-the-counter, is undergoing testing in cancer research due to its telomerase-inhibiting abilities. [ 26 ] A number of research groups have experimented with the use of telomerase inhibitors in animal models , and as of 2005 and 2006 phase I and II human clinical trials are underway.
The microrobots proved effective in tests with mice. In the two studies, "Fluorescent dye or cell membrane–coated nanoparticle functionalized algae motors were further embedded inside a pH-sensitive capsule" and "antibiotic-loaded neutrophil membrane-coated polymeric nanoparticles [were attached] to natural microalgae". [33] [34] [35]
A kit for the purification of plasmids—small ring-shaped DNA molecules in bacterial cells. [5] 1996 saw the initial public offering of QIAGEN on the technology-oriented Nasdaq stock exchange, becoming the first German company to do so. [6] 1997 saw the initial public offering on the Frankfurt Stock Exchange in Germany. [7]