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The common biomolecular mechanisms underlying addiction – CREB and ΔFosB – were reviewed by Eric J. Nestler in a 2013 review. [3] Genetics and mental disorders may precipitate the severity of a drug addiction. It is estimated that 50% of healthy individuals developing an addiction can trace the cause to genetic factors. [4]
The modern disease theory of alcoholism states that problem drinking is sometimes caused by a disease of the brain, characterized by altered brain structure and function. Today, alcohol use disorder (AUD) is used as a more scientific and suitable approach to alcohol dependence and alcohol -related problems.
According to the new disease model, rather than being a disease in the conventional sense, addiction is a disease of choice. That is, it is a disorder of the parts of the brain necessary to make proper decisions. As one becomes addicted to cocaine, the ventral tegmentum nucleus accumbens in the brain is the organ. [5]
Dr. Gene Heyman [14] and others assert alcoholism is not a progressive, incurable disease. See disease theory of alcoholism for a full discussion. The diagnostic assessment of alcoholism in someone can include an assessment of co-morbidity with conditions such as mental illness and domestic violence.
Peele maintains that, depending on the person, abstinence or moderation are valid approaches to treat excessive drinking. In a Psychology Today article which compared the Life Process Program with the disease model, [12] he also argues against the theory proposed decades ago by modern physicians, mental health professionals, research scientists, etc. that addiction is a disease. [13]
Hart opposes the brain disease model of addiction dominant in the field, which holds that addiction is a brain disorder. Nora Volkow, director of the National Institute on Drug Abuse, states that visible differences in the brains of addicts helps explain the nature of compulsive drug usage. Hart states that most studies show that drug users ...
Dodes received an A.B. from Dartmouth College in 1966, his D.M.S. from Dartmouth's Geisel School of Medicine in 1968, and his M.D. from Harvard Medical School in 1970. He is a training and supervising analyst emeritus of the Boston Psychoanalytic Society and Institute, and a retired assistant clinical professor of psychiatry at Harvard Medical School.
In general medicine and psychiatry, recovery has long been used to refer to the end of a particular experience or episode of illness.The broader concept of "recovery" as a general philosophy and model was first popularized in regard to recovery from substance abuse/drug addiction, for example within twelve-step programs or the California Sober method.