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They present as multiple small or large bumps characteristically on the heels and wrists. [2] Most are asymptomatic and pain is rare, although some may present with pain before the bumps are noticed. [3] They generally occur bilaterally and display a yellowish to skin-color. [3] They may feel soft or firm. [3] [4]
Overweight female dogs are especially prone to developing these tumors, and most older or overweight dogs have at least one lipoma. [46] [47] In dogs, lipomas usually occur in the trunk or upper limbs. [45] They are also found less commonly in cattle and horses, and rarely in cats and pigs.
Smaller (less than 0.5 cm) raised soft tissue bumps may be termed papules. [3] The evaluation of a skin nodule includes a description of its appearance, its location, how it feels to touch and any associated symptoms which may give clues to an underlying medical condition. [4] Nodules in skin include dermatofibroma [5] and pyogenic granuloma. [6]
Lipedema is classified by stage: Stage 1: Normal skin surface with enlarged hypodermis (lipedema fat). Stage 2: Uneven skin with indentations in fat and larger hypodermal masses (lipomas). Stage 3: Bulky extrusions of skin and fat cause large deformations especially on the thighs and around the knees.
It usually appears in adult life, and usually on the axilla, knee, ear, arm, scalp and the lower trunk. [3] In both multiple and solitary variants, the histopathology shows variable amounts of mature lipocytes within the dermis. Occasionally, there is an excessive fibrocollagenous tissue proliferation.
A noticeable lump in relation to an extremity may be the first presenting symptom. Multiple deformities can arise, namely coronal plane deformities around the knees, ankles, shoulders, elbows, and wrists. For example, genu valgum (knock knees), ankle valgus, ulnar bowing and shortening, and radial head subluxation are encountered.
A seborrheic keratosis is a non-cancerous skin tumour that originates from cells, namely keratinocytes, in the outer layer of the skin called the epidermis. Like liver spots, seborrheic keratoses are seen more often as people age. [4] The tumours (also called lesions) appear in various colours, from light tan to black.
Patients often perceive it as a lump or hard mass. It causes either pain or tenderness but only until it becomes large enough. This kind of tumor is commonly found in the extremities, especially around the knee, feet and ankle. Patients diagnosed with clear cell sarcoma are usually between the ages of 20 and 40. [1]