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Dietary supplements containing all eight are referred to as a vitamin B complex. Individual B vitamins are referred to by B-number or by chemical name, such as B 1 for thiamine , B 2 for riboflavin , and B 3 for niacin , [ 1 ] [ 2 ] while some are more commonly recognized by name than by number, such as pantothenic acid (B 5 ), biotin (B 7 ...
[2] Most fundamental are the cobalt complexes with only alkyl ligands. Examples include Co(4-norbornyl) 4 and its cation. [3] Alkylcobalt is represented by vitamin B 12 and related enzymes. In methylcobalamin the ligand is a methyl group, which is electrophilic. in vitamin B12, the alkyl ligand is an adenosyl group.
The structure of vitamin B 12 was the first low-molecular weight natural product determined by x-ray analysis rather than by chemical degradation. Thus, while the structure of this novel type of complex biomolecule was established, its chemistry remained essentially unknown; exploration of this chemistry became one of the tasks of the vitamin's chemical synthesis.
Vitamin B 12 is the most chemically complex of all vitamins. [6] [2] [7] Only some archaea and bacteria can synthesize vitamin B 12. [8] Vitamin B 12 deficiency is a widespread condition that is particularly prevalent in populations with low or no consumption of animal foods. [9]
Megavitamin-B 6 syndrome, also known as hypervitaminosis B 6, vitamin B 6 toxicity, and vitamin B 6 excess, [a] is a medical condition characterized by adverse effects resulting from excessive intake of vitamin B 6. [1] [2] [22] Primarily affecting the nervous system, this syndrome manifests through symptoms such as peripheral sensory ...
Historically, it was believed to be part of the vitamin B complex and was called vitamin B 13, but it is now known that it is not a vitamin. The compound is synthesized in the body via a mitochondrial enzyme, dihydroorotate dehydrogenase [ 2 ] or a cytoplasmic enzyme of pyrimidine synthesis pathway .
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