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  2. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    NSAID identification on label of generic ibuprofen, an over-the-counter non-steroidal anti-inflammatory drug. Non-steroidal anti-inflammatory drugs [1] [3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots.

  3. Naproxen - Wikipedia

    en.wikipedia.org/wiki/Naproxen

    Severe side effects include an increased risk of heart disease, stroke, gastrointestinal bleeding, and stomach ulcers. [8] The heart disease risk may be lower than with other NSAIDs. [8] It is not recommended in people with kidney problems. [8] Use is not recommended in the third trimester of pregnancy. [8] Naproxen is a nonselective COX ...

  4. Cyclooxygenase-2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cyclooxygenase-2_inhibitor

    The cause of the cardiovascular problems became, and remains, a subject of intensive research. [29] As of 2012 results have been converging on the hypothesis that the adverse cardiovascular effects are most likely due to inhibition of COX-2 in blood vessels , which leads to a decrease in the production of prostacyclin in them.

  5. Prostaglandin inhibitors - Wikipedia

    en.wikipedia.org/wiki/Prostaglandin_inhibitors

    Prostaglandin inhibitors are drugs that inhibit the synthesis of prostaglandin in human body. [1] There are various types of prostaglandins responsible for different physiological reactions such as maintaining the blood flow in stomach and kidney, regulating the contraction of involuntary muscles and blood vessels, and act as a mediator of inflammation and pain.

  6. Ketorolac - Wikipedia

    en.wikipedia.org/wiki/Ketorolac

    Like all NSAIDs, ketorolac can cause premature constriction of the ductus arteriosus in the infant if taken by the mother during the third trimester of pregnancy. [ 12 ] [ 13 ] In October 2020, the U.S. Food and Drug Administration (FDA) required the drug label to be updated for all nonsteroidal anti-inflammatory medications to describe the ...

  7. FDA approves new pain medication as an alternative to opioids ...

    www.aol.com/fda-approves-pain-medication...

    For the first time in two decades, the Food and Drug Administration (FDA) has approved a new class of medication that provides an alternative to addictive opioids for patients looking to manage ...

  8. Sulindac - Wikipedia

    en.wikipedia.org/wiki/Sulindac

    Like other NSAIDs, it is useful in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in the body to the active NSAID. More specifically, the agent is converted by liver enzymes to a sulfide that is excreted in the bile and then reabsorbed from the intestine.

  9. FDA approves opioid-free pain medication with 'no sign of ...

    www.aol.com/fda-approves-opioid-free-pain...

    A new opioid-free pain medication was approved by the U.S. Food and Drug Administration (FDA) on Thursday, marking a non-addictive alternative for patients.. Journavx (suzetrigine), made by Vertex ...

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