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Inflammation plays a major role in arteriosclerosis and arterial stiffness. [2] Increased arterial stiffness is associated with an increased risk of cardiovascular events such as myocardial infarction, hypertension, heart failure, and stroke. [3] [4] [5] The World Health Organization identified cardiovascular disease as the leading cause of ...
The arterial compliance - the amount of tension produced per stretch of arteries, decreases with age, and the stiffness of arteries increases with age. [3] The structural change in blood vessels causes the elderly to be more susceptible to hypertension, which leads to complications in arteries, the heart and even the brain. [citation needed]
Other causes include vasculitis and in situ thrombosis related to hypercoagulable states. [53] Additional mechanisms of peripheral artery disease include arterial spasm and fibromuscular dysplasia. [19] The cause and pathophysiology of arterial spasm are not fully understood, but it is hypothesised that they can occur secondary to trauma. [54]
Heavy legs is a condition described as an unpleasant sensation of pain and heaviness in the lower limbs. Symptoms include legs feeling weighted, stiff, and tired. Heavy legs can be caused by a wide-ranging collection of disorders including but not restricted to varicose veins, peripheral artery disease, restless legs syndrome, multiple sclerosis, venous insufficiency.
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...
Also arterial hyalinosis and arteriolar hyalinosis refers to thickening of the walls of arterioles by the deposits that appear as homogeneous pink hyaline material in routine staining. [3] It is a type of arteriolosclerosis, which refers to thickening of the arteriolar wall and is part of the aging process.
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Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries.This is a chronic inflammatory disease involving many different cell types and driven by elevated levels of cholesterol in the blood. [9]
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