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In 2020, PEA has been suggested as a drug that may prove beneficial for the treatment of lung inflammation caused by SARS-CoV-2 infection. [62] A pharmaceutical company called FSD Pharma have entered PEA into a Phase 1 clinical trial under the name FSD-201, and has approval from the FDA for progressing to Phase 2a for this indication. [63]
Phenethylamine [note 1] (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in ...
N-Methylphenethylamine (NMPEA) is a naturally occurring trace amine neuromodulator in humans that is derived from the trace amine, phenethylamine (PEA). [2] [3] It has been detected in human urine (<1 μg over 24 hours) [4] and is produced by phenylethanolamine N-methyltransferase with phenethylamine as a substrate, which significantly increases PEA's effects.
The pharmacokinetics of phenylethanolamine, after intravenous administration to dogs, were studied by Shannon and co-workers, who found that the drug followed the "two-compartment model", with T 1/2 (α) ≃ 6.8 mins and T 1/2 (β) ≃ 34.2 mins; the "plasma half-life" of phenylethanolamine was therefore about 30 minutes. [15]
β-Methylphenethylamine (β-Me-PEA, BMPEA, or 1-amino-2-phenylpropane) is an organic compound of the phenethylamine class, and a positional isomer of the drug amphetamine, with which it shares some properties. In particular, both amphetamine and β-methylphenethylamine are human TAAR1 agonists. [2]
You can also reach out to LNK International, the manufacturers of the over-the-counter medicine, at 1-800-426-9391 or email complaints-inquiries@lnkintl.com if you have any questions or concerns.
Phenethylamine (1-amino-2-phenyl ethane) is a monoamine compound. Substitutions to the phenethylamine molecule give rise to a group of compounds collectively known as substituted phenethylamines or phenethylamines .
Current required warning labels on alcohol sold in the U.S. say: "GOVERNMENT WARNING: (1) According to the Surgeon General, women should not drink alcoholic beverages during pregnancy because of ...