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Sertraline was developed by scientists at Pfizer and approved for medical use in the United States in 1991. It is on the World Health Organization's List of Essential Medicines [16] and available as a generic medication. [10] In 2016, sertraline was the most commonly prescribed psychotropic medication in the United States. [17]
The main indication for SSRIs is major depressive disorder; however, they are frequently prescribed for anxiety disorders, such as social anxiety disorder, generalized anxiety disorder, panic disorder, obsessive–compulsive disorder (OCD), eating disorders, chronic pain, and, in some cases, for posttraumatic stress disorder (PTSD).
In comparative studies of sertraline and other SSRIs, about 14 percent of people who were prescribed sertraline at a typical dose experienced diarrhea, compared to about seven percent of those on ...
Sertraline (Zoloft) Paroxetine (Paxil, Pexeva) ... One of the most commonly prescribed antidepressants, SSRIs are often used as a first line of treatment for several mental health conditions.
Sertraline. Sold under the brand name Zoloft, sertraline is a widely used SSRI that’s primarily prescribed to treat depression. It’s also used to treat anxiety disorders, including social ...
Among the 21 most commonly prescribed antidepressants, the most effective and well-tolerated are escitalopram, paroxetine, sertraline, agomelatine, and mirtazapine. [ 19 ] [ 20 ] For children and adolescents with moderate to severe depressive disorder, some evidence suggests fluoxetine (either with or without cognitive behavioral therapy ) is ...
This delay can explain the reason why antidepressants do not have effect on depression immediately. This can also be the reason why the antidepressant mechanisms can be connected to the increasing neuro impulse flow from 5-HT neurons, where as the concentration of 5-HT increases at the axon terminal before SSRIs start to work properly.
Sertraline (Zoloft) As an SSRI antidepressant, escitalopram is commonly prescribed to treat depression. The FDA also approves it for the treatment of generalized anxiety disorder (GAD).
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