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Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly). Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.
Autopsy: Cardiomegaly has been suggested when the heart weighs more than >399 grams in women and >449 grams in men. [8] Large intestine: Dilation Upper limit of normal range of diameter: [9] Cecum: 10.5 cm; Ascending colon: 7.0 cm; Transverse colon: 6.5 cm; descending colon and sigmoid colon: 6.8 cm; Rectum near rectal/sigmoid junction: 7.5 cm ...
Hepatomegaly is enlargement of the liver. [4] It is a non-specific medical sign, having many causes, which can broadly be broken down into infection, hepatic tumours, and metabolic disorder. Often, hepatomegaly presents as an abdominal mass. Depending on the cause, it may sometimes present along with jaundice. [1]
Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...
Portal vein thrombosis causes upper abdominal pain, possibly accompanied by nausea and an enlarged liver and/or spleen; the abdomen may be filled with fluid (). [3]A persistent fever may result from the generalized inflammation. [1]
Patients with lymphocytic interstitial pneumonia may present with lymphadenopathy, enlarged liver, enlarged spleen, enlarged salivary gland, thickening and widening of the extremities of the fingers and toes , and breathing symptoms such as shortness of breath and wheezing.
Signs (including enlarged liver and spleen) and symptoms (including headache and vomiting) of acute HIV infection Signs and symptoms are diagnostic indications of an illness , injury, or condition. Signs are objective and externally observable; symptoms are a person's reported subjective experiences.
The cutaneous form presents with skin ulcers, while the mucocutaneous form presents with ulcers of the skin, mouth, and nose. The visceral form starts with skin ulcers and later presents with fever, low red blood cell count, and enlarged spleen and liver. [2] [3] Infections in humans are caused by more than 20 species of Leishmania.