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Nalmefene, sold under the brand name Revex among others, is a medication that is used in the treatment of opioid overdose and alcohol dependence. [2] [3] Nalmefene belongs to the class of opioid antagonists and can be taken by mouth, administered by injection, or delivered through nasal administration.
Alcohol intoxication, commonly described in higher doses as drunkenness or inebriation, [9] and known in overdose as alcohol poisoning, [1] is the behavior and physical effects caused by recent consumption of alcohol.
The preferred antidote is fomepizole, with ethanol used if this is not available. Hemodialysis may also be used in those where there is organ damage or a high degree of acidosis. Other treatments may include sodium bicarbonate, folate, and thiamine. [2] Outbreaks of methanol ingestion have occurred due to contamination of drinking alcohol.
Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol use or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. [8] It has also been found effective in the treatment of other addictions and may be used for them off-label. [12]
Opioid overdose reversal drug Narcan will be available over the counter to buy at drug stores, supermarkets and convenience stores. Opioid overdose antidote Narcan will be widely available over ...
Vermont, a state with a long waiting list for medically based drug treatment, suspended a doctor’s license over incomplete paperwork. As doctors face scrutiny from the DEA, states have imposed even greater regulations severely limiting access to the medications, according to a 2014 report commissioned by the federal agency SAMHSA.
Alcohol has been used as an antiseptic as early as 1363, with evidence to support its use becoming available in the late 1800s. [ 32 ] At times and places of poor public sanitation (such as medieval Europe ), the consumption of alcoholic drinks was a way of avoiding water-borne diseases such as cholera .
The Food and Drug Administration is pushing for drugmakers to apply for over-the-counter approval for naloxone, the opioid overdose antidote.
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