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C is a coefficient for the expected percentage of weight made up of free water. For adult, non-elderly males, C = 0.6. For adult elderly males, malnourished males, or females, C = 0.5. For adult elderly or malnourished females, C = 0.45. A total body water deficit (TBWD) can then be approximated by the following formula:
The adult human body averages ~53% water. [7] This varies substantially by age, sex, and adiposity. In a large sample of adults of all ages and both sexes, the figure for water fraction by weight was found to be 48 ±6% for females and 58 ±8% water for males. [8]
Free water clearance can be used as an indicator of how the body is regulating water. A free water clearance of zero means the kidney is producing urine isosmotic with respect to the plasma. Values greater than zero imply that the kidney is producing dilute urine through the excretion of solute-free water.
The recommended daily amount of drinking water for humans varies. [1] It depends on activity, age, health, and environment.In the United States, the Adequate Intake for total water, based on median intakes, is 4.0 litres (141 imp fl oz; 135 US fl oz) per day for males older than 18, and 3.0 litres (106 imp fl oz; 101 US fl oz) per day for females over 18; it assumes about 80% from drink and 20 ...
In lean healthy adult men, the total body water is about 60% (60–67%) of the total body weight; it is usually slightly lower in women (52–55%). [2] [3] The exact percentage of fluid relative to body weight is inversely proportional to the percentage of body fat. A lean 70 kg (150 lb) man, for example, has about 42 (42–47) liters of water ...
Plasma osmolality measures the body's electrolyte–water balance. [1] There are several methods for arriving at this quantity through measurement or calculation. Osmolality and osmolarity are measures that are technically different, but functionally the same for normal use.
Diagram depicting the distribution of total body water into percentages of intracellular and extracellular fluid. [18] Water content of a human body varies from 70-75% in newborns to 40% and less in obese adults, [19] an average value of 60% is suggested. [20] Within the body, water is classified as intracellular fluid or extracellular fluid.
A wide variety of body composition measurement methods exist. The gold standard measurement technique for the 4-compartment model consists of a weight measurement, body density measurement using hydrostatic weighing or air displacement plethysmography, total body water calculation using isotope dilution analysis, and mineral content measurement by dual-energy X-ray absorptiometry (DEXA). [1]