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1. Artery blockages are a serious reason for leg pain at night. Perhaps the most worrisome diagnosis are artery blockages (“ peripheral artery disease “). Many people with poor circulation have leg pain when walking or calf pain when walking. This is called intermittent claudication.
The primary cause of PAD is atherosclerosis, a condition caused by plaque buildup in your arteries, which narrows and blocks arteries, significantly reducing blood flow. The pain intensifies at night due to the decreased blood circulation while lying down.
In PAD, the legs or arms — usually the legs — don't get enough blood flow to keep up with demand. This may cause leg pain when walking, called claudication, and other symptoms.
A frequent indicator of artery blockage in the legs is pain or cramping, especially during activities like walking or climbing. This discomfort, referred to as intermittent claudication, occurs...
Leg pain at night may indicate a severe blockage in the arteries leading to the lower extremities, known as critical limb ischemia (CLI). Symptoms of CLI include leg pain, open, non-healing sores (arterial ulcers), thickened toenails, shiny skin on the legs, diminished leg pulse, and dry gangrene (dry, black skin) in the affected area.
If you have a lot of swelling in your legs, there’s likely an early blockage in the arteries at the level of your femoral arteries. Because the femoral artery typically supplies blood to the thighs, this can lead to pain such as burning or stinging at night or when you run or walk.
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