Search results
Results from the WOW.Com Content Network
PEG 400 is strongly hydrophilic. The partition coefficient of PEG 400 between hexane and water is 0.000015 (log P = − 4.8 {\displaystyle P=-4.8} ), indicating that when PEG 400 is mixed with water and hexane, there are only 15 parts of PEG400 in the hexane layer per 1 million parts of PEG 400 in the water layer.
Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation. [6] Macrogol (with brand names such as Laxido, Movicol and Miralax) is the generic name for polyethylene glycol used as a laxative. The name may be followed by a number that ...
The attachment of an inert and hydrophilic polymer was first reported around 1970 to extend blood life and control immunogenicity of proteins. [12] Polyethylene glycol was chosen as the polymer. [13] [14] In 1981 Davis and Abuchowski founded Enzon, Inc., which brought three PEGylated drugs to market. Abuchowski later founded and is CEO of ...
The PEG coating consists of hydrophilic molecules that are repulsive to protein adsorption. [11] Proteins consist of hydrophobic molecules and charge sites that want to bind to other hydrophobic molecules and oppositely charged sites. [12] By applying a thin monolayer coating of PEG, protein adsorption is prevented at the device site.
Poloxamer 407 is a hydrophilic non-ionic surfactant of the more general class of copolymers known as poloxamers.Poloxamer 407 is a triblock copolymer consisting of a central hydrophobic block of polypropylene glycol flanked by two hydrophilic blocks of polyethylene glycol (PEG).
[citation needed] The presence of valence cations in the solution impedes the polymer's ability to bond with the water molecule. The SAP's total absorbency and swelling capacity are controlled by the type and degree of cross-linkers used to make the gel. Low-density cross-linked SAPs generally have a higher absorbent capacity and swell to a ...
When consecutively measuring amino acids of a protein, changes in value indicate attraction of specific protein regions towards the hydrophobic region inside lipid bilayer. The hydrophobic or hydrophilic character of a compound or amino acid is its hydropathic character, [1] hydropathicity, or hydropathy.
Crystal structure of a first-generation polyphenylene dendrimer reported by Müllen et al [5] A first-generation "cyanostar" dendrimer and its STM image [6]. The first dendrimers were made by divergent synthesis approaches by Fritz Vögtle in 1978, [7] R.G. Denkewalter at Allied Corporation in 1981, [8] [9] Donald Tomalia at Dow Chemical in 1983 [10] and in 1985, [11] [12] and by George R ...