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Macrophages are found in essentially all tissues, [4] where they patrol for potential pathogens by amoeboid movement. They take various forms (with various names) throughout the body (e.g., histiocytes, Kupffer cells, alveolar macrophages, microglia, and others), but all are part of the mononuclear phagocyte system.
Smoker's macrophages affect the elastic fibers in the mucus layer of the airways, tightening the lumen and causing asthma. Symptoms of asthma include wheezing, coughing, and chest discomfort. To ameliorate the situation, drugs that either suppress the inflammatory response or relaxes the airway will be administrated, so air can pass through. [22]
Macrophage activation syndrome; Maffucci syndrome; Majeed syndrome; Majewski's polydactyly syndrome; Mal de debarquement; Malformative syndrome; Mallory–Weiss syndrome; Malnutrition–inflammation complex; Malouf syndrome; Malpuech facial clefting syndrome; Management of chronic headaches; Manning criteria; Marchiafava–Bignami disease ...
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been ... human: macrophage migration ...
Monocyte- and macrophage-related cutaneous conditions are characterized histologically by infiltration of the skin by monocyte or macrophage cells, [10] often divided into several categories, including granulomatous disease, [83] histiocytoses, [84] and sarcoidosis. [85] Actinic granuloma (O'Brien granuloma)
There is uncontrolled activation and proliferation of macrophages, and T lymphocytes, with a marked increase in circulating cytokines, such as IFN-gamma, and GM-CSF. The underlying causative event is unclear, and is the subject of ongoing research. In many cases of MAS, a decreased natural killer cell (NK-cell) function is found.
While IL-1β is released by monocytes and macrophages, it is also present in nociceptive DRG neurons. IL-6 plays a role in neuronal reaction to an injury. TNF-α is a well known proinflammatory cytokine present in neurons and the glia. TNF-α is often involved in different signaling pathways to regulate apoptosis in the cells.