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2. Keratin - Wikipedia

   en.wikipedia.org/wiki/Keratin

   Alpha-keratin (α-keratin) is a type of keratin found in vertebrates. It is the key structural material making up scales, hair, nails, feathers, horns, claws, hooves, and the outer layer of skin among vertebrates. Keratin also protects epithelial cells from damage or stress. Keratin is extremely insoluble in water and organic solvents.

3. List of cutaneous conditions caused by mutations in keratins

   en.wikipedia.org/wiki/List_of_cutaneous...

   Cutaneous conditions caused by mutations in keratin proteins Defective keratin type Condition(s) 1: Epidermolytic hyperkeratosis Ichthyosis hystrix of Curth–Macklin Diffuse nonepidermolytic palmoplantar keratoderma (Unna–Thost keratoderma) Diffuse epidermolytic palmoplantar keratoderma (Vörner keratoderma) 2 (2e) Ichthyosis bullosa of ...

4. List of keratins - Wikipedia

   en.wikipedia.org/wiki/List_of_keratins

   The first sequences of keratins revealed that keratins could be grouped into two categories based on their sequence homologies. [1] [2] These two groups of keratins were named as type I and type II keratins. [2]

5. List of keratins expressed in the human integumentary system

   en.wikipedia.org/wiki/List_of_keratins_expressed...

   Keratin protein expression within the various layers and anatomic locations of the human integumentary system Keratin type Location of expression 1: Suprabasal epidermis of skin 2 (2e) Granular layer: 3: Cornea: 4: Suprabasal epidermis of mucosa 5: Basal layer: 6a: Suprabasal palmoplantar skin 6b: Basal palmoplantar skin Nail bed Hair follicle ...

6. Alpha-keratin - Wikipedia

   en.wikipedia.org/wiki/Alpha-keratin

   Alpha-keratin, or α-keratin, is a type of keratin found in mammalian vertebrates. This protein is the primary component in hairs , horns , claws , nails and the epidermis layer of the skin . α-keratin is a fibrous structural protein , meaning it is made up of amino acids that form a repeating secondary structure.

7. Hyperkeratosis - Wikipedia

   en.wikipedia.org/wiki/Hyperkeratosis

   Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis, or skin), often associated with the presence of an abnormal quantity of keratin, [1] and is usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed ...

8. Keratinocyte - Wikipedia

   en.wikipedia.org/wiki/Keratinocyte

   A number of structural proteins (filaggrin, keratin), enzymes (e.g. proteases), lipids, and antimicrobial peptides contribute to maintain the important barrier function of the skin. Keratinization is part of the physical barrier formation ( cornification ), in which the keratinocytes produce more and more keratin and undergo terminal ...

9. Human skin - Wikipedia

   en.wikipedia.org/wiki/Human_skin

   The human skin is the outer covering of the body and is the largest organ of the integumentary system. ... The cytoplasm is released and the protein keratin is inserted.