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Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
What Your PSA Test Results Mean THE PSA IS a good initial “check engine light” for the prostate, says Garrett Pohlman , M.D., a urologist and host of The Prostate Health Podcast.
These tests in combination with the initial PSA can help us determine who may benefit most from further investigation such as a prostate biopsy. By the age of 50, men should be having prostate ...
The other is a PSA blood test, which measures the amount of a protein that’s produced by cancerous and noncancerous cells in the prostate. “Elevated PSA levels can be an indicator of prostate ...
Prostate-specific antigen. Prostate-specific antigen (PSA) is secreted by the epithelial cells of the prostate gland and can be detected in a sample of blood. [14] PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. [15]
Those with elevated PSA may undergo secondary screening blood tests that measure subtypes of PSA and other molecules to better predict the likelihood that a person will develop aggressive prostate cancer. Many measure "free PSA" – the fraction of PSA unbound to other blood proteins, usually around 10% to 30%.
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