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Piceol is used in the synthesis of several pharmaceutical drugs including octopamine, sotalol, bamethan, and dyclonine. [citation needed] Piceol can be used to make acetaminophen by condensation with hydroxylamine and subsequent Beckmann rearrangement in acid. [4] Anticonvulsants are also possible by Mannich reaction: [5]
4-Hydroxyacetophenone (p-hydroxyacetophenone, piceol) This page was last edited on 27 February 2021, at 08:40 (UTC). Text is available under the Creative Commons ...
Acetophenone is formed as a byproduct of the cumene process, the industrial route for the synthesis of phenol and acetone.In the Hock rearrangement of isopropylbenzene hydroperoxide, migration of a methyl group rather than the phenyl group gives acetophenone and methanol as a result of an alternate rearrangement of the intermediate:
The 4 substrates of this enzyme are (4-hydroxyphenyl)ethan-1-one, NADPH, H +, and O 2, whereas its 3 products are hydroquinone acetate ester, NADP +, and H 2 O. This enzyme belongs to the family of oxidoreductases , specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen.
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It undergoes rapid polymerization, including forming a hemiacetal cyclic dimer.Under alkaline conditions, it undergoes a rapid aldol condensation.. Hydroxyacetone can be produced by degradation of various sugars.
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3-Hydroxyacetophenone is a chemical compound. It is a component of castoreum, the exudate from the castor sacs of the mature beaver. [1] Related compounds.