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The chemical compound is an anti-coagulant with active half-life longer than warfarin and other synthetic 1,3-indandione anticoagulants. [3] [4] It is toxic to mammals, in all forms; exposure and oral ingestion of the toxin may cause irregular heartbeat and major maladies associated with its impact on blood clotting, depending on dose. [5]
1,3-Indandione (sometimes simply indanedione) is an organic compound with the molecular formula C 6 H 4 (CO) 2 CH 2. It is a β-diketone with indane as its structural nucleus. It is a colorless or white solid, but old samples can appear yellowish [ 3 ] or even green.
Pindone is an anticoagulant drug [3] for agricultural use. It is commonly used as a rodenticide in the management of rat and rabbit populations. It is pharmacologically analogous to warfarin and inhibits the synthesis of Vitamin K -dependent clotting factors .
6. Worms and other parasitic infections. With heavy worm burdens or certain parasitic infections, dogs can vomit. You may see worms in the vomit, but an absence of worms doesn’t mean parasites ...
If a person or pet has sudden, unexplained illness after swimming or signs of poisoning, call a medical provider or veterinarian right away or the Texas Poison Control Center at 800-222-1222.
It has a sweet taste and thus dogs will drink it. As little as 2 1/2 tablespoons can kill a medium-sized dog in 2–3 days. This type of poisoning is often fatal as dog owners do not know their pet has ingested the antifreeze. De-icing fluids can also contain ethylene glycol. Paraquat is used for weeding and grass control.
Anisindione (brand name Miradon) is a synthetic anticoagulant and an 1,3-indandione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins. [1]
Most dogs, however, will need radiation, chemotherapy, and other medications. Even with those therapies, the survival time is short, so ivermectin could help if it proves to be useful.
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