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The schematic summary of the production method. To produce hydrogel fiber, the solidification of the pregel solution is the most important step. The pregel solution needs to be solidified while maintaining its fibrous shape. To achieve this, several methods based on chemical crosslinking, phase change, rheological property change have been ...
Peptide hydrogel formation shown by the inverted vial method. A hydrogel is a biphasic material, a mixture of porous and permeable solids and at least 10% of water or other interstitial fluid. [1] [2] The solid phase is a water insoluble three dimensional network of polymers, having absorbed a large amount of water or biological fluids.
Self-healing hydrogels are a specialized type of polymer hydrogel.A hydrogel is a macromolecular polymer gel constructed of a network of crosslinked polymer chains. Hydrogels are synthesized from hydrophilic monomers by either chain or step growth, along with a functional crosslinker to promote network formation.
The synthesis of nanocomposite hydrogels is a process that requires specific material and method. These polymers need to be made up of equally spaced out, 30 nm in diameter, clay platelets that can swell and exfoliate in the presence of water.
Diverse methods are employed to manipulate the initiation, propagation, and termination rates during chain polymerization. A related issue is temperature control, also called heat management, during these reactions, which are often highly exothermic. For example, for the polymerization of ethylene, 93.6 kJ of energy are released per mole of ...
The characterization of mechanical properties in polymers typically refers to a measure of the strength, elasticity, viscoelasticity, and anisotropy of a polymeric material. The mechanical properties of a polymer are strongly dependent upon the Van der Waals interactions of the polymer chains, and the ability of the chains to elongate and align ...
Drug-loaded dextran cross-linked hydrogel. Dextran hydrogels and dextran conjugate hydrogels are heavily cross-linked polymeric networks that have a strong affinity for water. These gels have soft, elastic physical properties and are biocompatible and biodegradable. [1] Dextran hydrogels have also been shown to be stable and safe in vivo. [2]
For example, Makhmalzadeh et al. proposed an ultrasound-triggered drug delivery method involving the use of thermo-responsive hydrogels loaded with silibinin, a cancer drug for treating melanoma. [ 16 ] [ 41 ] At low temperatures, these thermo-responsive hydrogels exist in liquid form but following ultrasonication, they transition into a gel state.