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  2. Microscopic polyangiitis - Wikipedia

    en.wikipedia.org/wiki/Microscopic_polyangiitis

    The signs and symptoms of microscopic polyangiitis may resemble those of granulomatosis with polyangiitis (GPA) (another form of small-vessel vasculitis) but typically lacks the significant upper respiratory tract involvement (e.g., sinusitis) frequently seen in people affected by GPA. [citation needed]

  3. Vasculitis - Wikipedia

    en.wikipedia.org/wiki/Vasculitis

    Non-specific symptoms are common and include fever, headache, fatigue, myalgia, weight loss, and arthralgia. [5] [6] All forms of vasculitis, even large vessel vasculitides, may cause skin manifestations. The most common skin manifestations include purpura, nodules, livedo reticularis, skin ulcers, and purpuric urticaria. [7]

  4. p-ANCA - Wikipedia

    en.wikipedia.org/wiki/P-ANCA

    ANCA will less commonly form against alternative antigens that may also result in a p-ANCA pattern. These include lactoferrin, elastase, and cathepsin G. [citation needed] When the condition is a vasculitis, the target is usually MPO. [1] However, the proportion of p-ANCA sera with anti-MPO antibodies has been reported to be as low as 12%. [2]

  5. Systemic vasculitis - Wikipedia

    en.wikipedia.org/wiki/Systemic_vasculitis

    Small vessel vasculitis (SVV) is separated into immune complex SVV and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). [4] Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a necrotizing vasculitis linked to MPO-ANCA or PR3-ANCA that primarily affects small vessels and has few or no immune deposits.

  6. Anti-neutrophil cytoplasmic antibody - Wikipedia

    en.wikipedia.org/wiki/Anti-neutrophil_cytoplasm...

    Atypical ANCA is associated with drug-induced systemic vasculitis, inflammatory bowel disease and rheumatoid arthritis. [3] [7] The ANCA-positive rate is much higher in patients with type 1 diabetes mellitus than in healthy individuals. [8] Levamisole, which is a common adulterant of cocaine, can cause an ANCA positive vasculitis. [9]

  7. Pauci-immune - Wikipedia

    en.wikipedia.org/wiki/Pauci-immune

    In the setting of systemic vasculitis as described above, proliferative nephritis is associated with antineutrophil cytoplasmic antibodies (ANCA). [3] Because of this, an ANCA test should always follow a negative immunofluorescence result to have the highest accuracy for confirming pauci-immune vasculitis-driven proliferative nephritis.

  8. Wikipedia:Osmosis/Vasculitis - Wikipedia

    en.wikipedia.org/wiki/Wikipedia:Osmosis/Vasculitis

    Churg-Strauss syndrome is very similar to both granulomatosis with polyangiitis and microscopic polyangiitis. It too is caused by p-ANCA antibodies and it causes similar symptoms such as sinusitis, lung damage, and kidney damage, but it also causes gastrointestinal, skin, nerve, and heart damage like some medium-vessel vasculitis diseases.

  9. Granulomatosis with polyangiitis - Wikipedia

    en.wikipedia.org/wiki/Granulomatosis_with...

    It is an autoimmune disease and a form of vasculitis that affects small- and medium-size vessels in many organs but most commonly affects the upper respiratory tract, lungs and kidneys. [6] The signs and symptoms of GPA are highly varied and reflect which organs are supplied by the affected blood vessels.