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4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene (MBP) is a metabolite of bisphenol A (BPA). [1] MBP has potent estrogenic activity in vitro and in vivo , up to thousandfold stronger than BPA. [ 2 ] It may also play a role in neuronal cell apoptosis [ 3 ] and may increase risk for several forms of cancer.
The NH 2-terminal extension decreases the folding rate of the precursor form of MBP relative to its mature form by at least 5 fold, but it has no effect on the unfolding rate. [ 6 ] [ 7 ] The equilibrium unfolding of MBP can be modelled by a two-state mechanism with a stability ∆G(H 2 O) equal to 9.45 kcal mol −1 at 25 °C, pH 7.6.
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Mega base pairs (Mbp) Major basic protein, a protein which in humans is encoded by the PRG2 gene; Maltose-binding protein, a part of the maltose/maltodextrin system of Escherichia coli; 4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a metabolite of bisphenol A; Milk basic protein, a milk protein fraction
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17195 Ensembl ENSG00000165471 ENSMUSG00000024863 UniProt P11226 P41317 RefSeq (mRNA) NM_000242 NM_001378373 NM_001378374 NM_010776 NM_001365058 RefSeq (protein) NP_000233 NP_001365302 NP_001365303 NP_034906 NP_001351987 Location (UCSC) Chr 10: 52.77 – 52.77 Mb Chr 19: 30.21 – 30.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Mannose-binding lectin (MBL), also called mannan ...
Milk basic protein (MBP) is a fraction of whey protein found in milk. [1] Separated from milk through the process of fractionation , it is a functional compound [ 2 ] and consists of several milk proteins which are biologically active.
Myelin basic protein (MBP) is a protein believed [weasel words] to be important in the process of myelination of nerves in the nervous system.The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. [5]
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