Search results
Results from the WOW.Com Content Network
Chloramphenicol is a broad-spectrum antibiotic that typically stops bacterial growth by stopping the production of proteins. [5] Chloramphenicol was discovered after being isolated from Streptomyces venezuelae in 1947. [8] Its chemical structure was identified and it was first synthesized in 1949.
IARC group 2A agents are substances and exposure circumstances that have been classified as probable carcinogens by the International Agency for Research on Cancer (IARC). [1] This designation is applied when there is limited evidence of carcinogenicity in humans, as well as sufficient evidence of carcinogenicity in experimental animals .
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product. The other sections are as follows:
Mutagenic effects; Reproductive effects; Tumorigenic effects; Acute toxicity; Other multiple dose toxicity; Specific numeric toxicity values such as LD 50, LC 50, TDLo, and TCLo are noted as well as species studied and the route of administration used. For all data the bibliographic source is listed. The studies are not evaluated in any way.
Examples of amphenicols include chloramphenicol, thiamphenicol, azidamfenicol, and florfenicol. The first-in-class compound was chloramphenicol, introduced in 1949. Chloramphenicol was initially discovered as a natural product and isolated from the soil bacteria Streptomyces venezuelae; [2] however, all amphenicols are now made by chemical ...
Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. [1] It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids.
An example SDS, including guidance for handling a hazardous substance and information on its composition and properties. A safety data sheet (SDS), [1] material safety data sheet (MSDS), or product safety data sheet (PSDS) is a document that lists information relating to occupational safety and health for the use of various substances and products.
Common forms of antibiotic misuse include excessive use of prophylactic antibiotics in travelers and failure of medical professionals to prescribe the correct dosage of antibiotics on the basis of the patient's weight and history of prior use. Other forms of misuse include failure to take the entire prescribed course of the antibiotic ...