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Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. [18] It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura ...
Polysomnography (PSG) is a multi-parameter type of sleep study [1] and a diagnostic tool in sleep medicine.The test result is called a polysomnogram, also abbreviated PSG.The name is derived from Greek and Latin roots: the Greek πολύς (polus for "many, much", indicating many channels), the Latin somnus ("sleep"), and the Greek γράφειν (graphein, "to write").
In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. Abbreviations include K in, [1] K 0, [2] or R 0.
Pulsus paradoxus is not related to pulse rate or heart rate, and it is not a paradoxical rise in systolic pressure. Normally, blood pressure drops less precipitously than 10 mmHg during inhalation. Pulsus paradoxus is a sign that is indicative of several conditions, most commonly pericardial effusion .
When occurring in sleep, RMD episodes are more likely to onset during non-REM, stage 2 sleep. Roughly 46% of sleep-RMD episodes occur only in non-REM sleep; 30% in non-REM and REM; and only 24% strictly in REM sleep. [12] Most patients are unresponsive during an episode and are unlikely to remember the movements occurring upon awakening.
The number of hours of sleep is variable, however the proportion of sleep spent in a particular stage remains mostly consistent; healthy adults normally spend 20–25% of their sleep in REM sleep. [5] During rest following a sleep-deprived state, there is a period of rebound sleep which has longer and deeper episodes of SWS to make up for the ...
[5] [6] When occurring as a result of a medication, it is also known as an infusion reaction. [ 1 ] The term cytokine storm is often used interchangeably with CRS but, despite the fact that they have similar clinical phenotype , their characteristics are different.
During respiration, the intermittent vagus nerve activation occurs, which results in beat to beat variations in the resting heart rate. During inspiration vagal tone is slowed down and the heart rate goes up (being maximal at the peak of inspiration), while during expiration vagal tone is increased and heart rate decreases, being slowest at end-expiration.