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Arachnoid granulations (also arachnoid villi, and Pacchionian granulations or bodies) are small outpouchings of the arachnoid mater and subarachnoid space into the dural venous sinuses of the brain. The granulations are thought to mediate the draining of cerebrospinal fluid (CSF) from the subarachnoid space into the venous system .
The arachnoid mater covering the brain is referred to as the arachnoidea encephali, and the portion covering the spinal cord as the arachnoidea spinalis. The arachnoid and pia mater are sometimes considered as a single structure, the leptomeninx, or the plural version, leptomeninges (lepto, from the Greek root meaning "thin" or "slender").
On either side of it are several depressions for the arachnoid granulations, and at its back part, the openings of the parietal foramina when these are present. It is crossed in front by the coronal suture and behind by the lambdoid suture, while the sagittal suture lies in the medial plane between the parietal bones.
These sinuses play a crucial role in cerebral venous drainage. A dural venous sinus, in human anatomy, is any of the channels of a branching complex sinus network that lies between layers of the dura mater, the outermost covering of the brain, and functions to collect oxygen-depleted blood. Unlike veins, these sinuses possess no muscular coat.
The year 1705 was a special time in Pacchioni's life: he was appointed head physician at the ancient Ospedaledi S. Giovanni in Laterano, and published the original description of arachnoid granulations in his Dissertatio Epistolaris de Glandulis Conglobatis Durae Meningis Humanae.
Arachnoid (astrogeology), a geological structure found only on the planet Venus; Arachnoid (botany), referring to organs with a cobwebby exterior appearance; Arachnoid granulation, small protrusions of the arachnoid mater; Arachnoid mater, a layer of the meninges, membranes that contain the central nervous system
The subdural space (or subdural cavity) is a potential space that can be opened by the separation of the arachnoid mater from the dura mater as the result of trauma, pathologic process, or the absence of cerebrospinal fluid as seen in a cadaver.
The bases of denticulate ligaments arise in the pia mater and are firmly attached to the arachnoid mater and dura mater at the apex. [2] The denticulate ligaments extend across the subarachnoid space between anterior nerve roots and posterior nerve roots, piercing the intervening spinal arachnoid mater to reach the dura. [1]