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  2. Genetic recombination - Wikipedia

    en.wikipedia.org/wiki/Genetic_recombination

    [citation needed] While in this formation, homologous sites on two chromatids can closely pair with one another, and may exchange genetic information. [6] Because there is a small probability of recombination at any location along a chromosome, the frequency of recombination between two locations depends on the distance separating them.

  3. Homologous recombination - Wikipedia

    en.wikipedia.org/wiki/Homologous_recombination

    In RNA viruses, homologous recombination can be either precise or imprecise. In the precise type of RNA-RNA recombination, there is no difference between the two parental RNA sequences and the resulting crossover RNA region. Because of this, it is often difficult to determine the location of crossover events between two recombining RNA sequences.

  4. Gene conversion - Wikipedia

    en.wikipedia.org/wiki/Gene_conversion

    Gene conversion is the process by which one DNA sequence replaces a homologous sequence such that the sequences become identical after the conversion. [1] Gene conversion can be either allelic, meaning that one allele of the same gene replaces another allele, or ectopic, meaning that one paralogous DNA sequence converts another.

  5. Bivalent (genetics) - Wikipedia

    en.wikipedia.org/wiki/Bivalent_(genetics)

    The search for the homologous target, helped by numerous proteins collectively referred as the synaptonemal complex, cause the two homologs to pair, between the leptotene and the pachytene phases of meiosis I. [4] Resolution of the DNA recombination intermediate into a crossover exchanges DNA segments between the two homologous chromosomes at a ...

  6. Homologous chromosome - Wikipedia

    en.wikipedia.org/wiki/Homologous_chromosome

    Homologous chromosomes can repair this damage by aligning themselves with chromosomes of the same genetic sequence. [16] Once the base pairs have been matched and oriented correctly between the two strands, the homologous chromosomes perform a process that is very similar to recombination, or crossing over as seen in meiosis.

  7. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    A cell is said to be homozygous for a particular gene when identical alleles of the gene are present on both homologous chromosomes. [2] An individual that is homozygous-dominant for a particular trait carries two copies of the allele that codes for the dominant trait. This allele, often called the "dominant allele", is normally represented by ...

  8. Chromosomal crossover - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_crossover

    Crossing over occurs between prophase I and metaphase I and is the process where two homologous non-sister chromatids pair up with each other and exchange different segments of genetic material to form two recombinant chromosome sister chromatids. It can also happen during mitotic division, [1] which may result in loss of heterozygosity.

  9. Gene knockout - Wikipedia

    en.wikipedia.org/wiki/Gene_knockout

    Homologous recombination is the exchange of genes between two DNA strands that include extensive regions of base sequences that are identical to one another. In eukaryotic species, bacteria, and some viruses, homologous recombination happens spontaneously and is a useful tool in genetic engineering.