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In medicine and medical statistics, the gold standard, criterion standard, [1] or reference standard [2] is the diagnostic test or benchmark that is the best available under reasonable conditions. [3] It is the test against which new tests are compared to gauge their validity, and it is used to evaluate the efficacy of treatments. [1]
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
[1] [2] In clinical practice, verification bias is more likely to occur when a preliminary diagnostic test is negative. Because many gold standard tests can be invasive, expensive, and carry a higher risk (e.g. angiography, biopsy, surgery), patients and physicians may be more reluctant to undergo further work-up if a preliminary test is negative.
However, electron microscopy is highly versatile due to its ability to analyze any type of sample and identify any type of virus. Therefore, it remains the gold standard for identifying viruses that do not show up on routine diagnostic tests or for which routine tests present conflicting results. [7]
From left to right: 0.5, 1, and 2 McFarland standards Testing based on exposing bacteria to antibiotics uses agar plates or dilution in agar or broth. [ 9 ] The selection of antibiotics will depend on the organism grown, and the antibiotics that are available locally. [ 5 ]
The Berg Balance Scale is used by clinical exercise physiologists, physiotherapists and occupational therapists to determine the functional mobility of an individual. This test can be administered prior to treatment for elderly individuals and patients with a history of but not limited to stroke, [1] Multiple sclerosis, Parkinson's disease, Ataxia, vertigo, cardiovascular disease and ...
Gold Standard Laboratories or GSL was an independent record label which was founded in 1993 in Boulder, Colorado by Sonny Kay. In 2000, it was relocated to San Diego, California, United States, and two years later, to Los Angeles. It was headquartered in L.A. until closing its doors on October 29, 2007. [1] [2]
With confirmatory Western blot, the chance of a false-positive identification in a low-prevalence setting is about 1 in 250 000 (95% CI, 1 in 173 000 to 1 in 379 000). The specificity rate given here for the inexpensive enzyme immunoassay screening tests indicates that, in 1,000 HIV test results of healthy individuals, about 15 of these results ...