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Vitamins B 6, B 9, or B 12 supplements (alone or combined) lower homocysteine level and might slightly reduce the risk of stroke but not of myocardial infarction compared to standard care or placebo in clinical trials. [5]
The remethylation process that detoxifies homocysteine and converts it back to methionine can occur via either of two pathways. The pathway present in virtually all cells involves the enzyme methionine synthase (MS), which requires vitamin B 12 as a cofactor, and also depends indirectly on folate and other B vitamins.
“Whole-grain toast or cereal provides B vitamins, which may help lower homocysteine and risk for heart disease. Rolled oats are known to lower serum cholesterol as well.” ...
Deficiency of vitamin B 12 can impair the remethylation of homocysteine in the methionine cycle, and result in raised homocysteine levels. [65] There is much evidence linking elevated homocysteine concentrations with an increased risk of cardiovascular disease, [ 66 ] and homocysteine lowering treatments have led to improvements in ...
Cyanocobalamin is the most common form used in dietary supplements and food fortification because cyanide stabilizes the molecule against degradation. Methylcobalamin is also offered as a dietary supplement. [12] There is no advantage to the use of adenosylcobalamin or methylcobalamin forms for the treatment of vitamin B 12 deficiency. [20] [21 ...
Research has linked B-vitamins (like B6, B12, and folate) to reducing risk of cognitive decline due to potential memory boosting benefits, says Jaclyn London, M.S., R.D., C.D.N.
In the body, homocysteine can be recycled into methionine or converted into cysteine with the aid of vitamin B 6, B 9, and B 12. [3] High levels of homocysteine in the blood (hyperhomocysteinemia) is regarded as a marker of cardiovascular disease, likely working through atherogenesis, which can result in ischemic injury.
It’s rich in vitamins B6 and B12 as well as choline. ... Several studies have found that people who eat more omega-3s from fish have a lower risk of developing Alzheimer’s disease, dementia ...
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