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Hyperpolarized gas MRI, also known as hyperpolarized helium-3 MRI or HPHe-3 MRI, is a medical imaging technique that uses hyperpolarized gases to improve the sensitivity and spatial resolution of magnetic resonance imaging (MRI). This technique has many potential applications in medicine, including the imaging of the lungs and other areas of ...
Hyperpolarized 129 Xe gas magnetic resonance imaging is a medical imaging technique used to visualize the anatomy and physiology of body regions that are difficult to image with standard proton MRI. In particular, the lung, which lacks substantial density of protons, is particularly useful to be visualized with 129 Xe gas MRI. This technique ...
Traditional MRI generates poor images of lung tissue because there are fewer water molecules with protons that can be excited by the magnetic field. Using hyperpolarized gas an MRI scan can identify ventilation defects in the lungs. Before the scan, a patient is asked to inhale hyperpolarized xenon mixed with a buffer gas of helium or nitrogen ...
Xenon-129 is a safe inert noble gas that can be used to quantify lung function. With a single 10-second breath hold, hyperpolarized Xenon-129 is used with MRI to enable 3-dimensional lung imaging. [35] Xenon MRI is being used to monitor patients with pulmonary-vascular, obstructive, or fibrotic lung disease. [36]
Hyperpolarized carbon-13 MRI is a functional medical imaging technique for probing perfusion and metabolism using injected substrates. It is enabled by techniques for hyperpolarization of carbon-13 -containing molecules using dynamic nuclear polarization and rapid dissolution to create an injectable solution.
Xenon, particularly hyperpolarized 129 Xe, is a useful contrast agent for magnetic resonance imaging (MRI). In the gas phase, it can image cavities in a porous sample, alveoli in lungs, or the flow of gases within the lungs. [177] [178] Because xenon is soluble both in water and in hydrophobic solvents, it can image various soft living tissues.
In vivo magnetic resonance spectroscopy (MRS) is a specialized technique associated with magnetic resonance imaging (MRI). [1] [2]Magnetic resonance spectroscopy (MRS), also known as nuclear magnetic resonance (NMR) spectroscopy, is a non-invasive, ionizing-radiation-free analytical technique that has been used to study metabolic changes in brain tumors, strokes, seizure disorders, Alzheimer's ...
An MRI pulse sequence in magnetic resonance imaging (MRI) is a particular setting of pulse sequences and pulsed field gradients, resulting in a particular image appearance. [ 1 ] A multiparametric MRI is a combination of two or more sequences, and/or including other specialized MRI configurations such as spectroscopy .