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The editors-in-chief of the scientific journal Climacteric state that the greatest difference in function between bioidentical and synthetic hormones may be found in progesterone's behavior compared with progestin.
Androgens – bioidentical testosterone and dehydroepiandrosterone (DHEA), and synthetic anabolic steroids like methyltestosterone and nandrolone decanoate [116] [117] Tibolone – a synthetic medication available in Europe but not the United States– is more effective than placebo but less effective than combination hormone therapy in ...
Therapy can take the form of an estrogen pill, skin patch, ring, gel, cream, or spray, and it usually includes a second hormone, progestogen, which can be either progesterone or a synthetic progestin.
[23] [24] Aside from dose adjustment to account for the difference in molecular weight, oral estradiol valerate is considered to be equivalent to oral estradiol. [4] Because estradiol valerate is a prodrug of estradiol, it is considered to be a natural and bioidentical form of estrogen. [16] [17] [18
“Products like ours, formulated with bioidentical synthetic neuropeptides that mimic the same protein found in snake venom, temporarily relax fine lines by acting on the calcium channels in muscle."
[3] [4] Norgestimate is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. [1] It has very weak androgenic activity and no other important hormonal activity. [1] The medication is a prodrug of norelgestromin and to a lesser extent of ...
When used orally at high dosages, for instance as a form of high-dose estrogen therapy in men with prostate cancer and in women with breast cancer, synthetic and non-bioidentical estrogens like EE and diethylstilbestrol are associated with fairly high rates of severe cardiovascular complications such as VTE, myocardial infarction, and stroke.
Only a few clinical studies have assessed differences between oral CEEs and oral estradiol in terms of health parameters. [32] Oral CEEs have been found to possess a significantly greater risk of thromboembolic and cardiovascular complications than oral estradiol (OR Tooltip Odds ratio = 2.08) and oral esterified estrogens (OR Tooltip Odds ...
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