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Depression is a major cause of morbidity and mortality worldwide, as the epidemiology has shown. [1] Lifetime prevalence estimates vary widely, from 3% in Japan to 17% in India. Epidemiological data shows higher rates of depression in the Middle East, North Africa, South Asia and the United States than in other regions and countries. [2]
Social predictors of depression are aspects of one's social environment that are related to an individual developing major depression.These risk factors include negative social life events, conflict, and low levels of social support, all of which have been found affect the likelihood of someone experiencing major depression, the length of the depression, or the severity of the symptoms.
One reason depression is thought to be a pathology is that it causes so much psychic pain and distress. However, physical pain is also very distressful, yet it has an evolved function: to inform the organism that it is being damaged, to motivate it to withdraw from the source of damage, and to learn to avoid such damage-causing circumstances in the future.
The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
Depression is a significant mental illness with physiological and psychological consequences, including sluggishness, diminished interest and pleasure, and disturbances in sleep and appetite. [1] It is predicted that by the year 2030, depression will be the number one cause of disability in the United States and other high-income countries. [2]
A major depressive episode (MDE) is a period characterized by symptoms of major depressive disorder.Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities.
Depression can have multiple, sometimes overlapping, origins. Depression can be a symptom of some mood disorders, some of which are also commonly called depression, such as major depressive disorder, bipolar disorder and dysthymia. [7] Additionally, depression can be a normal temporary reaction to life events, such as the loss of a loved one.
Many of the environmental events that contribute to an extinction vortex do so through reduction in population size. These events can include rapid loss of population size due to disease, natural disasters, and climate change. Habitat loss and/or habitat degradation can also kick start an extinction vortex.
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