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The glomerulus and its surrounding Bowman's capsule constitute a renal corpuscle, the basic filtration unit of the kidney. [2] The rate at which blood is filtered through all of the glomeruli, and thus the measure of the overall kidney function, is the glomerular filtration rate .
The renal corpuscle is composed of two structures, the glomerulus and the Bowman's capsule. [3] The glomerulus is a small tuft of capillaries containing two cell types. Endothelial cells, which have large fenestrae, are not covered by diaphragms. Mesangial cells are modified smooth muscle cells that lie between the capillaries.
The glomerular basement membrane of the kidney is the basal lamina layer of the glomerulus.The glomerular endothelial cells, the glomerular basement membrane, and the filtration slits between the podocytes perform the filtration function of the glomerulus, separating the blood in the capillaries from the filtrate that forms in Bowman's capsule. [1]
In zoology, the trilobite Fenestraspis possessed extensive fenestrae in the posterior part of the body. [8] In the Paleognathae, there is an ilio–ischiatic fenestra. Fenestrae are also used to distinguish the three types of amniote: The ancestor of the amniotes is a primitive lizard, Hylonomus. From this reptile, three groups of amniotes ...
The cortex and medulla of the kidney contain nephrons, [21] each of which consists of a glomerulus and a complex tubular system. [22] The cortex contains glomeruli and is responsible for filtering the blood. [7] The medulla is responsible for urine concentration [23] and contains tubules with short and long loops of Henle. [24]
Each nephron begins in a renal corpuscle, which is composed of a glomerulus enclosed in a Bowman's capsule. Cells, proteins, and other large molecules are filtered out of the glomerulus by a process of ultrafiltration , leaving an ultrafiltrate that resembles plasma (except that the ultrafiltrate has negligible plasma proteins ) to enter Bowman ...
Glomerulus (/ ɡ l ə ˈ m ɛr (j) əl ə s, ɡ l oʊ-/; pl.: glomeruli) is a common term used in anatomy to describe globular structures of entwined vessels, fibers, or neurons. Glomerulus is the diminutive of the Latin glomus, meaning "ball of yarn". Glomerulus may refer to: Glomerulus (kidney), the filtering unit of the kidney
Bowman's capsule (or the Bowman capsule, capsula glomeruli, or glomerular capsule) is a cup-like sac at the beginning of the tubular component of a nephron in the mammalian kidney that performs the first step in the filtration of blood to form urine.
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