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Lipedema is a condition that is almost exclusively found in women [3] and results in enlargement of both legs due to deposits of fat under the skin. [2] Women of any weight may be affected [2] [3] and the fat is resistant to traditional weight-loss methods. [4]
Vastly more women than men have the condition, which causes accumulation of unusual deposits of adipose tissue predominately in the legs and arms, according to the Lipedema Foundation. According ...
The condition is commonly associated with vascular and cardiac changes associated with aging but can be caused by many other conditions, including congestive heart failure, kidney failure, liver cirrhosis, portal hypertension, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, a compromised lymphatic system or merely long periods of time sitting or standing ...
It can also occur in patients with increased hydrostatic venous pressure or decreased oncotic venous pressure, due to obstruction of lymphatic or venous vessels draining the lower extremity. Certain drugs (for example, amlodipine) can cause pedal edema. Cerebral edema is extracellular fluid accumulation in the brain. [1]
What it looks like: Purplish lesions on the inner arms, legs, wrists, or ankles can signify lichen planus, a skin rash triggered by an overreaction of the immune system.
Adiposis dolorosa is an outdated term for many years used synonymously as Dercum's disease, lipedema or Anders disease. [1] While there are numerous references to adiposis dolorosa, it is recommended that the term no longer be used. Dercum's is now recognized as a separate condition, as is lipedema. [2] [3]
Lymphedema, also known as lymphoedema and lymphatic edema, is a condition of localized swelling caused by a compromised lymphatic system. [2] The lymphatic system functions as a critical portion of the body's immune system and returns interstitial fluid to the bloodstream.
Elephantiasis, often incorrectly called elephantitis, is the enlargement and hardening of limbs or body parts due to tissue swelling (). [1] [2] It is characterised by edema, hypertrophy, and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels (). [2]