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Weakness is symmetric, progressive, and proximal (on or close to the torso), usually affecting the hip girdle and shoulder girdle muscles. [1] [3] Hip weakness can manifest as a waddling gate. [1] Shoulder weakness can manifest as winged scapulas. [1] Muscle contractures, especially of the Achilles tendon, and scoliosis can also occur. [1]
Proximal muscles are weak, and there is difficulty in climbing upstairs and getting up from a squatting position. [13] As a result of demineralization, the bones become less rigid. Physical signs include deformities like triradiate pelvis [ 14 ] and lordosis .
Explicitly, LGMD preferentially affects muscles of the hip girdle, thigh, shoulder girdle, and/or upper arm. [8] [6] The muscle weakness is generally symmetric. [11] Usually, the hip girdle is the first area to exhibit weakness, [2] manifesting as difficulty walking, going up and/or down stairs, rising from a chair, bending at the waist, or ...
Pelvic weakness can manifest as a Trendelenburg's sign. [4] Weakness of the back of the thigh (hamstrings) is more common than weakness of the front of the thigh (quadriceps). [4] In more severe cases, especially infantile FSHD, there can be anterior pelvic tilt, with associated hyperextension of the knees. [41]
Muscle weakness can also be classified as either "proximal" or "distal" based on the location of the muscles that it affects. Proximal muscle weakness affects muscles closest to the body's midline, while distal muscle weakness affects muscles further out on the limbs. Proximal muscle weakness can be seen in Cushing's syndrome [18] and ...
Trendelenburg gait, first described by Friedrich Trendelenburg in 1895, [1] is an abnormal human gait caused by an inability to maintain the pelvis level while standing on one leg. It is caused by weakness or ineffective action of the gluteus medius and gluteus minimus muscles.
Overall, you can lose between 1 to 3 inches in height as you age, per Medline Plus. While age-related height loss is normal, there are times when it's a sign of an underlying health condition.
Becker muscular dystrophy (BMD) is an X-linked recessive inherited disorder characterized by slowly progressing muscle weakness of the legs and pelvis. It is a type of dystrophinopathy . [ 5 ] [ 3 ] The cause is mutations and deletions in any of the 79 exons encoding the large dystrophin protein , essential for maintaining the muscle fiber's ...