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The signs and symptoms of oral cancer depend on the location of the tumor but are generally thin, irregular, red and/or white patches in the mouth. The classic warning sign is a persistent rough patch with ulceration , and a raised border that is minimally painful.
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Head and neck cancer can present a wide range of symptoms depending on where the cancer developed. These can include an ulcer in the mouth that does not heal, changes in the voice , difficulty swallowing , red or white patches in the mouth , and a neck lump .
Leukoplakia is a firmly attached white patch on a mucous membrane which is associated with increased risk of cancer. [4] [5] The edges of the lesion are typically abrupt and the lesion changes with time. [4] [6] Advanced forms may develop red patches. [6] There are generally no other symptoms. [9]
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Ulcers may act as a site for local infection and a portal of entry for oral flora that, in some instances, may cause septicaemia (especially in immunosuppressed patients). Therefore, oral mucositis can be a dose-limiting condition, disrupting a patient’s optimal cancer treatment plan and consequentially decreasing their chances of survival. [5]
Red, erosive or ulcerative lesions indicate atrophy, loss of epithelium and inflammation. [7] Early, acute lesions may be erythematous (red) and edematous (swollen). [ 2 ] With months and years of sun exposure, the lesion becomes chronic and may be grey-white in color and appear dry, scaly and wrinkled.
Oropharyngeal cancer, [1] [2] [3] also known as oropharyngeal squamous cell carcinoma and tonsil cancer, [1] is a disease in which abnormal cells with the potential to both grow locally and spread to other parts of the body are found in the oral cavity, in the tissue of the part of the throat that includes the base of the tongue, the tonsils, the soft palate, and the walls of the pharynx.
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