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Acne (/ˈækni/ ACK-nee), also known as acne vulgaris, is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles. [10] Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and possible scarring.
So when there’s excess sebum, it’s a dream for bacteria — a dream that can cause severe acne. Bacteria that gets into the hair follicle and becomes inflamed or infected results in deep ...
Isotretinoin is the only available acne drug that affects all four major pathogenic processes in acne, which distinguishes it from alternative treatments (such as antibiotics) and accounts for its efficacy in severe, nodulocystic cases. [85]
Acne conglobata is a severe, inflammatory variant of acne. Inflammatory papules, papulonodules, nodules and pustules may coalesce, and abscesses in the skin may form sinuses that interconnect. [4] Bleeding or draining of acneiform plaques may be present. The systemic findings seen in acne fulminans are not present.
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In addition to testosterone, isotretinoin may also precipitate acne fulminans, possibly related to highly increased levels of C acnes antigens in the patient's immune system. [3] Acne fulminans is a rare disease. Over the past several years, fewer cases of this disease have occurred, possibly because of earlier and better treatment of acne.
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Nodulocystic lesions are uncommon. In contrast to acne , these lesions can appear anywhere on the body, not just on the face. When the cause is a drug eruption, the individual will usually specify that the lesions go away once the medication is stopped.
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