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  2. Promethazine - Wikipedia

    en.wikipedia.org/wiki/Promethazine

    Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold [ 4 ] and may also be used for sedating people who are agitated or anxious, an effect that has led to ...

  3. Lean (drug) - Wikipedia

    en.wikipedia.org/wiki/Lean_(drug)

    Lean or purple drank (known by numerous local and street names) is a polysubstance drink used as a recreational drug.It is prepared by mixing prescription-grade cough or cold syrup containing an opioid drug and an anti-histamine drug with a soft drink and sometimes hard candy.

  4. Over-the-counter drug - Wikipedia

    en.wikipedia.org/wiki/Over-the-counter_drug

    Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, [1] as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription. In many countries, OTC drugs are selected by a regulatory agency to ensure that they ...

  5. H1 antagonist - Wikipedia

    en.wikipedia.org/wiki/H1_antagonist

    The most common adverse effect is sedation; this "side-effect" is utilized in many OTC sleeping-aid preparations. Other common adverse effects in first-generation H 1 -antihistamines include dizziness, tinnitus , blurred vision, euphoria , incoordination, anxiety , increased appetite leading to weight gain , insomnia , tremor, nausea and ...

  6. Sominex - Wikipedia

    en.wikipedia.org/wiki/Sominex

    Sominex is the trademarked name for several over the counter sleep aids. Different formulations of Sominex are available, depending upon the market. Both the US and UK formulations contain a significant dose of a first generation antihistamine with hypnotic properties.

  7. How To Decide Between Over-The-Counter and Prescription Hearing Aids. Unknown. Updated December 13, 2024 at 3:35 PM. On October 17, 2022, over-the-counter (OTC) ...

  8. Naproxen is considered to be the strongest anti-inflammatory medication available over the counter, says Walia. ... “Prescription NSAIDs generally have the same mechanism of action as OTC NSAIDs ...

  9. Chlorpromazine - Wikipedia

    en.wikipedia.org/wiki/Chlorpromazine

    In 1947, it synthesized promethazine, a phenothiazine derivative, which was found to have more pronounced sedative and antihistaminic effects than earlier drugs. [ 59 ] : 77 A year later, the French surgeon Pierre Huguenard used promethazine together with pethidine as part of a cocktail to induce relaxation and indifference in surgical patients.

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