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Firsocostat (formerly GS-976, ND-630, NDI-010976) is a potent allosteric ACC inhibitor, acting at the BC domain of ACC. [29] Firsocostat is under development in 2019 (Phase II) [ 30 ] by the pharmaceutical company Gilead as part of a combination treatment for non-alcoholic steatohepatitis (NASH), believed to be an increasing cause of liver failure.
Air Combat Command: Air National Guard Assistant to the Commander, Air Combat Command (ACC) Air National Guard (ANG) Major General Bryan E. Salmon [80] [a] U.S. Air Force: Air Combat Command: Mobilization Assistant to the Director of Operations, Air Combat Command (ACC) U.S. Air Force Reserve (AFR) Major General Mitchell A. Hanson [81] U.S. Air ...
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues.
The site of Mira Loma Air Force Station was originally constructed during World War II as the former Army Quartermaster Supply Depot at Mira Loma, California.. At Mira Loma Quartermaster Depot Colonel Charles E. Stafford established the Advance Communications Zone depot in January 1942, and on 5 June 1942 [1] activated the San Bernardino branch, California quartermaster depot, and the Mira ...
Lt Gen Francis H. Griswold: 3 May 1954: 30 June 1961 (1904–1989) [3] Designated as Vice Commander (1954–55) 5. Lt Gen John P. McConnell: 1 July 1961: 30 September 1962 (1908–1986) 6. Lt Gen Hunter Harris Jr. 1 October 1962: 31 July 1964 (1909–1987) 7. Lt Gen John Dale Ryan: 1 August 1964: 30 November 1964 (1915–1983) 8. Lt Gen Joseph ...
The Air Combat Command (ACC) is one of nine Major Commands (MAJCOMs) in the United States Air Force, reporting to Headquarters, United States Air Force (HAF) at the Pentagon. [9] It is the primary provider of air combat forces for the Air Force, and it is the direct successor to Tactical Air Command .
Kenneth Stephen Wilsbach [1] [2] (born c. 1963) is a United States Air Force general who serves as the commander of Air Combat Command. He previously served as the commander of Pacific Air Forces from 2020 to 2024.
In 1990, when Air Force Communications Service was disestablished as a major command, the 5th Group became part of Tactical Air Command, which was replaced by Air Combat Command in 1992. [3] In 2009, combat communications units, including the group, were made part of Air Force Space Command.