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Lipomas are rarely life-threatening, and the common subcutaneous lipomas are not a serious condition. Lipomas growing in internal organs can be more dangerous; for example, lipomas in the gastrointestinal tract can cause bleeding, ulceration, and painful obstructions (so-called "malignant by location", despite being a benign growth histologically).
Many discrete, encapsulated lipomas form on the trunk and extremities, with relatively few on the head and shoulders. [1] In 1993, a genetic polymorphism within lipomas was localized to chromosome 12q15 , where the HMGIC gene encodes the high-mobility-group protein isoform I-C. [ 2 ] This is one of the most commonly found mutations in solitary ...
The lipomas are well-encapsulated, slow-growing, benign fatty tumors. The distribution is defined as being focused in the trunk of the body and extremities. [2] Familial Multiple Lipomatosis can be identified when multiple lipomas occur in multiple family members that span different generations. [2] Some people may have hundreds of lipomas ...
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Lipomas are usually diagnosed clinically, although imaging (ultrasound, computed tomography, or magnetic resonance imaging) may be utilized to assist with the diagnosis of lipomas in atypical locations. [24] The main treatment for lipomas is surgical excision, after which the tumor is examined with histopathology to confirm the diagnosis. [24]
Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat across the body. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically recognizable features, signs, and symptoms that are characteristic of it and ...
Chondroid lipoma is an uncommon soft tissue fatty tumor that can develop in deeper or superficial tissues. It often manifests as a painless mass. [3] The subcutis, superficial muscular fascia, or skeletal muscles of the limbs and limb girdles, trunk, head, and neck are where the majority of lesions are located. [4]
The presence of eccrine sweat glands are used to distinguish the tumor from a common lipoma. Size and the development of the capsule (tissue surrounding the tumor) can also aid in diagnosis. Size and the development of the capsule (tissue surrounding the tumor) can also aid in diagnosis.