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Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is taken orally or intravenously for rheumatoid arthritis , psoriasis , Crohn's disease , nephrotic syndrome , eczema , and in organ transplants to prevent rejection .
Voclosporin, sold under the brand name Lupkynis, is a calcineurin inhibitor used as an immunosuppressant medication for the treatment of lupus nephritis. [2] [4] It is an analog of ciclosporin that has enhanced action against calcineurin and greater metabolic stability.
The term over-the-counter (OTC) refers to a medication that can be purchased without a medical prescription. [3] In contrast, prescription drugs require a prescription from a doctor or other health care professional and should only be used by the prescribed individual. [4]
Formulation of the drug for inhalation purposes has proved challenging because of ciclosporin's poor aqueous solubility. [5] Consequently, aerosol studies have often employed compatible solvents such as propylene glycol [6] or ethanol [7] as the vehicle for administration by nebulizer or have used more complicated aqueous-based formulations involving liposomes [8] [9] or other dispersions. [10]
Sometimes the term "depot tablet" is used, by analogy to the term for an injection formulation of a drug which releases slowly over time, but this term is not medically or pharmaceutically standard for oral medication. Modified-release dosage and its variants are mechanisms used in tablets (pills) and capsules to dissolve a drug over time in ...
Rhino pills and other non-prescription supplements aren’t regulated by the U.S. Food and Drug Administration (FDA) like medications are, and there’s rarely much science to back their claims ...
Ciclosporin exhibits insecticidal and antifungal properties [10] and is a key immunosuppressant drug used to prevent the rejection of transplanted organs. [13] Ciclosporin A also has the potential use in the treatment of autoimmune diseases. [10] The genome of filamentous T. inflatum contains a 12-gene cluster associated with a repetitive element.
Midol is a brand of over-the-counter analgesic drugs marketed for menstrual cramping and other effects related to premenstrual syndrome and menstruation. Various subbrands are formulated using different active ingredients. Midol is distributed by Bayer.