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Elastin-like polypeptides (ELPs) are synthetic biopolymers with potential applications in the fields of cancer therapy, tissue scaffolding, metal recovery, and protein purification. For cancer therapy, the addition of functional groups to ELPs can enable them to conjugate with cytotoxic drugs. [ 1 ]
Elastin is a protein encoded by the ELN gene in humans and several other animals. Elastin is a key component in the extracellular matrix of gnathostomes (jawed vertebrates). [ 5 ] It is highly elastic and present in connective tissue of the body to resume its shape after stretching or contracting. [ 6 ]
Cutis laxa and Williams syndrome have elastic matrix defects that have been directly associated with alterations in the elastin gene. Alpha-1 antitrypsin deficiency is a genetic disorder where elastin is excessively degraded by elastase, a degrading protein released by neutrophils during the inflammatory response.
Fibrous proteins consist of many families including keratin, collagen, elastin, fibrin or spidroin. Collagen is the most abundant of these proteins which exists in vertebrate connective tissue including tendon, cartilage, and bone. [2]
Selenium plays important roles in hormone function, a healthy metabolism, DNA synthesis and protection from oxidative damage and infection, notes the U.S. National Institutes of Health (NIH ...
How to Reset Female Hormones For Weight Loss. This article was reviewed by Craig Primack, MD, FACP, FAAP, MFOMA. Hormones can be helpful heroes, supporting the immune system and a healthy sleep ...
First, a quick refresher: Testosterone is an androgen or male hormone present in women and men (although it's naturally higher in the latter) that impacts fertility, sexual function, and the ...
Demosine can not only be found in elastin, but also in urine, plasma, sputum, and there are different ways to identify and measure these quantities. [9] This means that it is used as a biomarker for elastin degradation which can be a detection for chronic obstructive pulmonary disease (COPD). Desmosine is a potential biomarker for matrix ...