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Richter's transformation (RT), also known as Richter's syndrome, is the conversion of chronic lymphocytic leukemia (CLL) or its variant, small lymphocytic lymphoma (SLL), into a new and more aggressively malignant disease. [ 1] CLL is the circulation of malignant B lymphocytes with or without the infiltration of these cells into lymphatic or ...
Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. [1] It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL).
Frequency. 904,000 (2015) [ 6] Deaths. 60,700 (2015) [ 7] Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [ 2][ 8] Early on, there are typically no symptoms. [ 2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss ...
Mycosis fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, [ 1] is the most common form of cutaneous T-cell lymphoma. It generally affects the skin, but may progress internally over time. Symptoms include rash, tumors, skin lesions, and itchy skin.
Less than 1 per 100,000 per year. Chronic myelomonocytic leukemia ( CMML) is a type of leukemia, which are cancers of the blood-forming cells of the bone marrow. In adults, blood cells are formed in the bone marrow, by a process that is known as haematopoiesis. In CMML, there are increased numbers of monocytes and immature blood cells ( blasts ...
A complete blood count ( CBC ), also known as a full blood count ( FBC ), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood ...
Stage IV – any of the above with liver or spleen involvement. Stage V – any of the above with blood or bone marrow involvement. [1] Each stage is divided into either substage a, those without systemic symptoms; or substage b, those with systemic symptoms such as fever, loss of appetite, weight loss, and fatigue.
Hard lump with a scaly top or ulceration. [ 1] Cutaneous squamous-cell carcinoma ( cSCC ), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [ 10] cSCC typically presents as a hard lump with a scaly surface, though it ...