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A review in 2006 of the literature on use of benzodiazepine and nonbenzodiazepine hypnotics concluded that more research is needed to evaluate the long-term effects of hypnotic drugs. [85] The majority of the problems of benzodiazepines are related to their long-term use rather than their short-term use. [ 86 ]
Diazepam. Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. [14] It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. [14]
Acepromazine, acetopromazine, or acetylpromazine (commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2, number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was used in humans during the 1950s as an antipsychotic, [ 4 ] but is now almost exclusively used on animals as a sedative and antiemetic.
Compare Klonopin (clonazepam) and Valium (diazepam), two benzodiazepines used for anxiety, seizures, and more. Learn about their differences, benefits, risks, and how they work.
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses. The elimination half-life is how long it takes for half ...
They are prescribed to treat conditions such as anxiety disorders, insomnia, and seizures. The first benzodiazepine, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and was made available in 1960 by Hoffmann–La Roche , which followed with the development of diazepam (Valium) three years later, in 1963. [ 1 ]
Oxazepam is a short-to-intermediate-acting benzodiazepine. [7][8] Oxazepam is used for the treatment of anxiety, [9][10] insomnia, and to control symptoms of alcohol withdrawal syndrome. It is a metabolite of diazepam, prazepam, and temazepam, [11] and has moderate amnesic, anxiolytic, anticonvulsant, hypnotic, sedative, and skeletal muscle ...
Because clonazepam is effective in low milligram doses (0.5 mg clonazepam = 10 mg diazepam), [117] [118] it is said to be among the class of "highly potent" benzodiazepines. [119] The anticonvulsant properties of benzodiazepines are due to the enhancement of synaptic GABA responses, and the inhibition of sustained, high-frequency repetitive firing.
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