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The Purkinje fibers, named for Jan Evangelista Purkyně, (English: / p ɜːr ˈ k ɪ n dʒ i / pur-KIN-jee; [1] Czech: [ˈpurkɪɲɛ] ⓘ; Purkinje tissue or subendocardial branches) are located in the inner ventricular walls of the heart, [2] just beneath the endocardium in a space called the subendocardium.
Parallel fibers pass orthogonally through the Purkinje neuron's dendritic arbor, with up to 200,000 parallel fibers [6] forming a Granule-cell-Purkinje-cell synapse with a single Purkinje cell. Canonically, each adult Purkinje cell receives approximately 500 climbing fiber synapses, all originating from a single climbing fiber from the inferior ...
The bundle of His (BH) [1]: 58 or His bundle (HB) [1]: 232 (/ h ɪ s / "hiss" [2]) is a collection of heart muscle cells specialized for electrical conduction.As part of the electrical conduction system of the heart, it transmits the electrical impulses from the atrioventricular node (located between the atria and the ventricles) to the point of the apex of the fascicular branches via the ...
Purkinje fibers, located in the heart; The visual Purkinje effect of how human beings do not see color in dim light; Purkinje images, reflections of objects from the surface of the cornea, and from the anterior and posterior surfaces of the lens; Purkinje Incorporated, a company that develops healthcare information technology software and services
The bundle branches were separately described by Retzer and Braeunig as early as 1904, but their physiological function remained unclear and their role in the electrical conduction system of the heart remained unknown until Sunao Tawara published his monograph on Das Reizleitungssystem des Säugetierherzens (English: The Conduction System of the Mammalian Heart) in 1906. [4]
A premature ventricular contraction (PVC) is a common event where the heartbeat is initiated by Purkinje fibers in the ventricles rather than by the sinoatrial node. PVCs may cause no symptoms or may be perceived as a "skipped beat" or felt as palpitations in the chest. PVCs do not usually pose any danger. [1]
Purkyně is best known for his 1837 discovery of Purkinje cells, large neurons with many branching dendrites found in the cerebellum. He is also known for his discovery in 1839 of Purkinje fibres, the fibrous tissue that conducts electrical impulses from the atrioventricular node to all parts of the ventricles of the heart.
The funny current is highly expressed in spontaneously active cardiac regions, such as the sinoatrial node (SAN, the natural pacemaker region), the atrioventricular node (AVN) and the Purkinje fibres of conduction tissue. The funny current is a mixed sodium–potassium current that activates upon hyperpolarization at voltages in the diastolic ...