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Physiological ketosis is the non-pathological (normal functioning) elevation of ketone bodies that can result from any state of increased fatty acid oxidation including fasting, prolonged exercise, or very low-carbohydrate diets such as the ketogenic diet. [5] In physiological ketosis, serum ketone levels generally remain below 3 mM. [1]
While ketosis refers to any elevation of blood ketones, ketoacidosis is a specific pathologic condition that results in changes in blood pH and requires medical attention. The most common cause of ketoacidosis is diabetic ketoacidosis but it can also be caused by alcohol , medications, toxins, and rarely, starvation.
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His trial on a few epilepsy patients in 1921 was the first use of the ketogenic diet as a treatment for epilepsy. [ 10 ] Wilder's colleague, paediatrician Mynie Gustav Peterman , later formulated the classic diet, with a ratio of one gram of protein per kilogram of body weight in children, 10–15 g of carbohydrate per day, and the remainder of ...
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