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Polarizing microscopy and application of other crystallographic techniques have improved identification of different microcrystals including monosodium urate, calcium pyrophosphate dihydrate, calcium hydroxyapatite, and calcium oxalate. [1]
Microcrystalline hydroxyapatite and ossein-hydroxyapatite are forms of calcium phosphate used as a dietary supplement. [36] Bone meal as a calcium supplementation has largely been discontinued due to concerns of contamination with heavy metals such as lead, arsenic, mercury, and cadmium identified in the 1980s.
Up to 50% by volume and 70% by weight of human bone is a modified form of hydroxyapatite, known as bone mineral. [7] Carbonated calcium-deficient hydroxyapatite is the main mineral of which dental enamel and dentin are composed. Hydroxyapatite crystals are also found in pathological calcifications such as those found in breast tumors, [8] as ...
Milwaukee shoulder syndrome (MSS) (apatite-associated destructive arthritis/Basic calcium phosphate (BCP) crystal arthritis/rapid destructive arthritis of the shoulder) [1] is a rare [2] rheumatological condition similar to pseudogout, associated with periarticular or intra-articular deposition of hydroxyapatite or basic calcium phosphate (BCP) crystals.
Bone as a material is very complex because of its hierarchal structure in which characteristics vary across length scales. [94] [95] At the basic scale, bone is composed of an organic matrix of collagen type-I. [94] Collagen type-I molecules form a composite material with hydroxyapatite to make up collagen fibrils. [95]
Mönckeberg's arteriosclerosis, or Mönckeberg's sclerosis, is a non-inflammatory form of arteriosclerosis (artery hardening), which differs from atherosclerosis traditionally. Calcium deposits are found in the muscular middle layer of the walls of arteries (the tunica media) [1] with no obstruction of the lumen.
The benefits of bone broth can vary depending on the type and added ingredients, but generally it's rich in vitamins and minerals, Julia Zumpano, a registered dietitian with the Cleveland Clinic ...
In bone, mineralization starts from a heterogeneous solution having calcium and phosphate ions. The mineral nucleates, inside the hole area of the collagen fibrils, as thin layers of calcium phosphate, which then grow to occupy the maximum space available there. The mechanisms of mineral deposition within the organic portion of the bone are ...
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