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Muscimol (also known as agarin or pantherine) is one of the principal psychoactive constituents of Amanita muscaria and related species of mushroom. Muscimol is a potent and selective orthosteric agonist for the GABA A receptor [3] and displays sedative-hypnotic, depressant and hallucinogenic [citation needed] psychoactivity.
Ibotenic acid or (S)-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid, also referred to as ibotenate, is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere.
As with all other muscaroid mushrooms, Amanita chrysoblema yellow-orange variant [citation needed] contains ibotenic acid, and muscimol, two psychoactive constituents which can cause effects such as hallucinations, synaesthesia, euphoria, dysphoria and retrograde amnesia. The effects of muscimol and ibotenic acid most closely resemble that of ...
As with other Amanita muscaria, the inzengae variety contains ibotenic acid, and muscimol, two psychoactive constituents which can cause effects such as hallucinations, synaesthesia, euphoria, dysphoria and retrograde amnesia. The effects of muscimol and ibotenic acid most closely resemble that of any GABAergic compound, but with a dissociative ...
Amanita muscaria, commonly known as the fly agaric or fly amanita, [5] is a basidiomycete of the genus Amanita. It is a large white- gilled , white-spotted, and usually red mushroom. Despite its easily distinguishable features, A. muscaria is a fungus with several known variations, or subspecies .
Trace concentrations of muscarine are also found in Amanita muscaria, though the pharmacologically more relevant compound from this mushroom is the Z-drug-like alkaloid muscimol. A. muscaria fruitbodies contain a variable dose of muscarine, usually around 0.0003% fresh weight. This is very low and toxicity symptoms occur very rarely.
Muscarinic antagonist effects and muscarinic agonist effects counterbalance each other for homeostasis. Certain muscarinic antagonists can be classified into either long-acting muscarinic receptor antagonists ( LAMA s) or short-acting muscarinic receptor antagonists ( SAMA s), depending on when maximum effect occurs and for how long the effect ...
Amanita muscaria var. formosa, known as the yellow orange fly agaric, is a hallucinogenic and poisonous [1] basidiomycete fungus of the genus Amanita.This variety, which can sometimes be distinguished from most other A. muscaria by its yellow cap, is a European taxon, although several North American field guides have referred A. muscaria var. guessowii to this name. [2]
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