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  2. Belimumab - Wikipedia

    en.wikipedia.org/wiki/Belimumab

    Belimumab, sold under the brand name Benlysta, is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), [6] also known as B-lymphocyte stimulator (BLyS). [7] It is approved in the United States [ 8 ] and Canada, [ 9 ] and the European Union [ 5 ] to treat systemic lupus erythematosus and lupus nephritis.

  3. B-cell activating factor - Wikipedia

    en.wikipedia.org/wiki/B-cell_activating_factor

    Belimumab (Benlysta) is a monoclonal antibody developed by Human Genome Sciences and GlaxoSmithKline, with significant discovery input by Cambridge Antibody Technology, which specifically recognizes and inhibits the biological activity of B-Lymphocyte stimulator (BLyS) and is in clinical trials for treatment of Systemic lupus erythematosus and ...

  4. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    Benlysta: mab: human: B-cell activating factor (BAFF) Y: systemic lupus erythematosus without renal or CNS involvement Bemarituzumab [26] mab: humanized: FGFR2: gastric cancer or gastroesophageal junction adenocarcinoma Benralizumab [38] Fasenra: mab: humanized: CD125: Y: asthma Berlimatoxumab [26] mab: human: Staphylococcus aureus bi-component ...

  5. Slow and Steady Has Investors Fleeing - AOL

    www.aol.com/news/2012-02-28-slow-and-steady-has...

    Slow and steady might win the race, but it isn't a way to keep biotech investors' interest. As we approach a year after GlaxoSmithKline (NYS: GSK) and Human Genome Sciences' (NAS: HGSI) Benlysta ...

  6. Down 20%: Benylsta Not Ramping Fast Enough - AOL

    www.aol.com/news/2011-10-26-down-20-benylsta-not...

    Sales of Human Genome Sciences' (NAS: HGSI) new lupus drug Benylsta continues to grow -- just not fast enough to keep investors interest. The stock traded down more than 20% today after net sales ...

  7. Human Genome Sciences - Wikipedia

    en.wikipedia.org/wiki/Human_Genome_Sciences

    Benlysta received U.S. Food and Regulatory Administration approval for use in lupus in March 2011. Belimumab was being developed with GlaxoSmithKline , [ 4 ] Abthrax ( raxibacumab ) for anthrax was the subject of a contract with the US Government under Project BioShield. [ 5 ]

  8. Monoclonal antibody therapy - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_antibody_therapy

    Each antibody binds only one specific antigen. Monoclonal antibodies (mAbs) have varied therapeutic uses. It is possible to create a mAb that binds specifically to almost any extracellular target, such as cell surface proteins and cytokines.

  9. How Was Night Stalker Richard Ramirez Caught? All About the ...

    www.aol.com/night-stalker-richard-ramirez-caught...

    In the 1980s, a serial killer who local media named the Night Stalker, terrorized cities across L.A. County. Police eventually identified this violent criminal as Richard Ramirez, a drifter from ...

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