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General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
The extension of cellular immune response to the brainstem and spinal cord causes inflammation and necrosis of small meningeal vessels. [citation needed] In tertiary syphilis, reactivation of chronic latent infection may result in meningovascular syphilis, arising from endarteritis obliterans of
Syphilis has been known as "the great imitator", because it may cause symptoms similar to many other diseases. [2] [3] Syphilis is most commonly spread through sexual activity. [2] It may also be transmitted from mother to baby during pregnancy or at birth, resulting in congenital syphilis.
Syphilis is caused by the bacteria Treponema pallidum, according to the CDC, and is most commonly spread from one person to another through vaginal, anal and oral sex, but it can also be ...
Stage 4: Tertiary Stage - Most people with untreated syphilis do not develop tertiary syphilis, but when it does happen, many different organ systems are affected. These include the heart, blood ...
Syphilis is usually spread from direct contact with a syphilis sore during vaginal, anal or oral sex, according to the CDC, although it can also spread from an infected pregnant women to her ...
Tabes dorsalis is caused by demyelination by advanced syphilis infection (tertiary syphilis) when the primary infection by the causative spirochete bacterium, Treponema pallidum, is left untreated for an extended period of time (past the point of blood infection by the organism). [3]
An expert explains why. ... gonorrhea and syphilis — in Americans ages 55 to 64 have more than doubled over the past decade. Given that 1 in 6 people globally will be 60 and older by 2030, the ...
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