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Homologous desensitization also occurs with cytokine and other types of receptors, such as those of the epidermal growth factor receptor type, but in these cases desensitization is mediated by other types of receptor kinases. [2] Homologous desensitization serves to limit or restrain a cell's responses to stimuli.
Desensitization (from Latin "de-" meaning "removal" and "sensus" meaning "feeling" or "perception") is a psychology term related to the treatment or process that diminishes emotional responsiveness (reduced reaction) to a negative or aversive stimulus after repeated exposure.
While heterologous desensitization occurs rapidly at low agonist concentrations, homologous desensitization shows a dose dependent response and usually begins at significantly higher concentrations. [3] [4] Homologous desensitization serves as a mechanism for tachyphylaxis and helps organisms to maintain homeostasis.
In medicine, desensitization is a method to reduce or eliminate an organism's negative reaction to a substance or stimulus. In pharmacology , drug desensitization refers to two related concepts. First, desensitization may be equivalent to drug tolerance and refers to subjects' reactions (positive or negative) to a drug reducing following its ...
Systematic desensitization, (relaxation training paired with graded exposure therapy), is a behavior therapy developed by the psychiatrist Joseph Wolpe. It is used when a phobia or anxiety disorder is maintained by classical conditioning .
Meta Platforms' former chief operating officer, Sheryl Sandberg, was sanctioned by a judge on Tuesday for deleting emails related to litigation over Facebook's Cambridge Analytica privacy scandal ...
"Contact desensitization" intends to increase a behavior by imagining a reinforcing experience in connection with modeling the correct behavior. "Covert negative reinforcement " attempts to increase a behavior by connecting the termination of an aversive stimulus with increased production of a target behavior.
Nos. 12-3176, 12-3644 IN THE UNITED STATES COURT OF APPEALS FOR THE SECOND CIRCUIT CHRISTOPHER HEDGES, et al., Plaintiffs-Appellees, v. BARACK OBAMA, individually and as