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While the NCCIH notes that milk thistle supplements are generally safe and well tolerated in recommended doses, "taking too much milk thistle can cause side effects like bloating, gas, diarrhea or ...
This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs. Non-inclusion of an herb in this list does not imply that it is free of adverse effects.
Milk thistle is believed to give some remedy for liver diseases (e.g. viral hepatitis) and the extract, silymarin, is used in medicine. Mild gastrointestinal distress is the most common adverse event reported for milk thistle. The incidence is the same as for placebo. [10] A laxative effect for milk thistle has also been reported infrequently. [11]
Silibinin (), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others.
The treatment is a type of metabolic therapy that has no evidence of efficacy. [47] Hoxsey therapy – a treatment consisting of a caustic herbal paste for external cancers or a herbal mixture for "internal" cancers, combined with laxatives, douches, vitamin supplements and dietary changes. A review by the Memorial Sloan Kettering Cancer Center ...
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Recently, Silybum marianum or blessed milk thistle has been shown to protect the liver from amanita toxins and promote regrowth of damaged cells. [6] [better source needed] [7] Orellanine: This toxin generally causes no symptoms for 3–20 days after ingestion.
Use of milk thistle may cause stomach upset and produce allergic reactions in some people. [23] Eyelid edema, ocular pruritus, dry eye, diplopia, and blurred vision are among the reported complications based on registered side effects in the WHO global database of adverse drug reactions. [24]
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